Ted, the foul-mouthed, pot-smoking teddy bear, has married his longtime human girlfriend, Tami-Lynn, and a beautiful wedding it was. But as with most marriages between stuffed animals and human beings, the honeymoon ends all too soon, and after only a year, the newlyweds are already fighting. Naturally, the best remedy to soothe a decaying marriage and revitalize the spark is to bring a baby into the equation. But since Ted is lacking in the genitalia department, their choices are reduced to either adoption or artificial insemination.